Healthcare Informatics Research

Review Article

April 30, 2025

Large Language Models in Medicine: Clinical Applications, Technical Challenges, and Ethical Considerations

Kyu-Hwan Jung

Healthc Inform Res. 2025;31(2):114-124.

Objectives: This study presents a comprehensive review of the clinical applications, technical challenges, and ethical considerations associated with using large language models (LLMs) in medicine. Methods: A literature survey of peer-reviewed...

Original Article

April 30, 2025

Developing an Explainable Artificial Intelligence System for the Mobile-Based Diagnosis of Febrile Diseases Using Random Forest, LIME, and GPT

Kingsley F. Attai, Constance Amannah, Moses Ekpenyong, et al.

Healthc Inform Res. 2025;31(2):125-135.

Objectives: This study proposes a mobile-based explainable artificial intelligence (XAI) platform designed for diagnosing febrile illnesses. Methods: We integrated the interpretability offered by local interpretable model-agnostic explanations (LIME) and the explainability...

Original Article

April 30, 2025

LLM-Based Response Generation for Korean Adolescents: A Study Using the NAVER Knowledge iN Q&A Dataset with RAG

Junseo Kim, Seok Jun Kim, Junseok Ahn, et al.

Healthc Inform Res. 2025;31(2):136-145.

Objectives: This research aimed to develop a retrieval-augmented generation (RAG) based large language model (LLM) system that offers personalized and reliable responses to a wide range of concerns raised by...

Original Article

April 30, 2025

Consensus on the Potential of Large Language Models in Healthcare: Insights from a Delphi Survey in Korea

Ah-Ram Sul, Seihee Kim

Healthc Inform Res. 2025;31(2):146-155.

Objectives: Given the rapidly growing expectations for large language models (LLMs) in healthcare, this study systematically collected perspectives from Korean experts on the potential benefits and risks of LLMs, aiming...

Original Article

April 30, 2025

Generative AI-Based Nursing Diagnosis and Documentation Recommendation Using Virtual Patient Electronic Nursing Record Data

Hongshin Ju, Minsul Park, Hyeonsil Jeong, et al.

Healthc Inform Res. 2025;31(2):156-165.

Objectives: Nursing documentation consumes approximately 30% of nurses’ professional time, making improvements in efficiency essential for patient safety and workflow optimization. This study compares traditional nursing documentation methods with a...

Original Article

April 30, 2025

Advancing Korean Medical Large Language Models: Automated Pipeline for Korean Medical Preference Dataset Construction

Jean Seo, Sumin Park, Sungjoo Byun, et al.

Healthc Inform Res. 2025;31(2):166-174.

Objectives: Developing large language models (LLMs) in biomedicine requires access to high-quality training and alignment tuning datasets. However, publicly available Korean medical preference datasets are scarce, hindering the advancement of...

Original Article

April 30, 2025

Symptom and Sentiment Analysis of Older People with Cancer and Caregivers: A Text Mining Approach Using Korean Social Media Data

Kyunghwa Lee, Soomin Hong

Healthc Inform Res. 2025;31(2):175-188.

Objectives: This study examined the symptoms and emotions expressed by older adults with cancer and their caregivers in South Korean online cancer communities. It aimed to identify narrative patterns and...

Original Article

April 30, 2025

Generative Pre-trained Transformer: Trends, Applications, Strengths and Challenges in Dentistry: A Systematic Review

Sibyl Siluvai, Vivek Narayanan, Vinoo Subramaniam Ramachandran, et al.

Healthc Inform Res. 2025;31(2):189-199.

Objectives: The integration of large language models (LLMs), particularly those based on the generative pre-trained transformer (GPT) architecture, has begun to revolutionize various fields, including dentistry. Despite these promising applications,...

Original Article

April 30, 2025

Large Language Models for Pre-mediation Counseling in Medical Disputes: A Comparative Evaluation against Human Experts

Min Seo Kim, Jung Su Lee, Hyuna Bae

Healthc Inform Res. 2025;31(2):200-208.

Objectives: Assessing medical disputes requires both medical and legal expertise, presenting challenges for patients seeking clarity regarding potential malpractice claims. This study aimed to develop and evaluate a chatbot based...

Large Language Models in Medicine Jinwook Choi Healthc Inform Res. 2025;31(2):111-113. Editorial April 30, 2025 Full text PubReader ePub PDF	Large Language Models in Medicine: Clinical Applications, Technical Challenges, and Ethical Considerations Kyu-Hwan Jung Healthc Inform Res. 2025;31(2):114-124. Review Article April 30, 2025 Full text PubReader ePub PDF
Developing an Explainable Artificial Intelligence System for the Mobile-Based Diagnosis of Febrile Diseases Using Random Forest, LIME, and GPT Kingsley F. Attai, Constance Amannah, Moses Ekpenyong, et al. Healthc Inform Res. 2025;31(2):125-135. Original Article April 30, 2025 Full text PubReader ePub PDF	LLM-Based Response Generation for Korean Adolescents: A Study Using the NAVER Knowledge iN Q&A Dataset with RAG Junseo Kim, Seok Jun Kim, Junseok Ahn, et al. Healthc Inform Res. 2025;31(2):136-145. Original Article April 30, 2025 Full text PubReader ePub PDF Supplementary Material
Consensus on the Potential of Large Language Models in Healthcare: Insights from a Delphi Survey in Korea Ah-Ram Sul, Seihee Kim Healthc Inform Res. 2025;31(2):146-155. Original Article April 30, 2025 Full text PubReader ePub PDF Supplementary Material	Generative AI-Based Nursing Diagnosis and Documentation Recommendation Using Virtual Patient Electronic Nursing Record Data Hongshin Ju, Minsul Park, Hyeonsil Jeong, et al. Healthc Inform Res. 2025;31(2):156-165. Original Article April 30, 2025 Full text PubReader ePub PDF
Advancing Korean Medical Large Language Models: Automated Pipeline for Korean Medical Preference Dataset Construction Jean Seo, Sumin Park, Sungjoo Byun, et al. Healthc Inform Res. 2025;31(2):166-174. Original Article April 30, 2025 Full text PubReader ePub PDF	Symptom and Sentiment Analysis of Older People with Cancer and Caregivers: A Text Mining Approach Using Korean Social Media Data Kyunghwa Lee, Soomin Hong Healthc Inform Res. 2025;31(2):175-188. Original Article April 30, 2025 Full text PubReader ePub PDF
Generative Pre-trained Transformer: Trends, Applications, Strengths and Challenges in Dentistry: A Systematic Review Sibyl Siluvai, Vivek Narayanan, Vinoo Subramaniam Ramachandran, et al. Healthc Inform Res. 2025;31(2):189-199. Original Article April 30, 2025 Full text PubReader ePub PDF	Large Language Models for Pre-mediation Counseling in Medical Disputes: A Comparative Evaluation against Human Experts Min Seo Kim, Jung Su Lee, Hyuna Bae Healthc Inform Res. 2025;31(2):200-208. Original Article April 30, 2025 Full text PubReader ePub PDF Supplementary Material
Multi-Agent Approach for Sepsis Management Victor Iapascurta, Ion Fiodorov, Adrian Belii, et al. Healthc Inform Res. 2025;31(2):209-214. Case Report April 30, 2025 Full text PubReader ePub PDF